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Cerebral blood movement (CBF) will increase from rest to ∼60% of peak oxygen uptake (VO(2peak)) and thereafter decreases towards baseline on account of hyperventilation-induced hypocapnia and subsequent cerebral vasoconstriction. It is unknown what happens to CBF in older adults (OA), who experience a decline in CBF at relaxation coupled with a blunted ventilatory response during VO(2peak). In 14 OA (71 ± 10 year) and 21 younger controls (YA; 23 ± four years), we hypothesized that OA would expertise much less hyperventilation-induced cerebral vasoconstriction and due to this fact an attenuated reduction in CBF at VO(2peak). Incremental exercise was performed on a cycle ergometer, while bilateral center cerebral artery blood move velocity (MCA V (imply); transcranial Doppler ultrasound), coronary heart price (HR; ECG) and finish-tidal PCO(2) (P(ET)CO(2)) have been monitored continuously. Blood pressure (BP) was monitored intermittently. From rest to 50% of VO(2peak), regardless of higher elevations in BP in OA, the change in MCA V(imply) was higher in YA in comparison with OA (28% vs. 15%, respectively; P 70% of VO(2peak), the hyperventilation-induced declines in each P(ET)CO(2) (14 mmHg (YA) vs.
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