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These are rare circumstances - round 20 million folks in the UK and EEA had obtained the vaccine as of March sixteen and EMA had reviewed solely 7 cases of blood clots in multiple blood vessels (disseminated intravascular coagulation, DIC) and 18 cases of CVST. A causal hyperlink with the vaccine just isn't proven, however is possible and deserves additional analysis. The PRAC concerned consultants in blood disorders in its overview, and worked carefully with other health authorities including the UK’s MHRA which has experience with administration of this vaccine to round eleven million individuals. Overall the variety of thromboembolic events reported after vaccination, each in research before licensing and in stories after rollout of vaccination campaigns (469 reports, 191 of them from the EEA), was decrease than that expected in the overall population. This enables the PRAC to affirm that there is no such thing as a improve in overall threat of blood clots.
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